Acylation of the influenza hemagglutinin modulates fusion activity.

doi:10.1006/viro.1998.9286

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Article

Acylation of the influenza hemagglutinin modulates fusion activity.

Virology - 1 Sept 1998

Fischer C, Schroth-Diez B, Herrmann A, Garten W, Klenk H D

Abstract excerpt

The influenza virus hemagglutinin (HA) contains three highly conserved cysteine residues at positions 551, 559, and 562 close to the carboxyl-terminus of the HA2 subunit which serve as palmitylation sites. Wild-type HA of influenza virus A/FPV/Rostock/34 (H7N1) and HA permutated by exchange of th...

Topics

Acylation
Amino Acid Sequence
Animals
Cells, Cultured
Chlorocebus aethiops
Giant Cells
Hemagglutinin Glycoproteins, Influenza Virus
Influenza A virus
Membrane Fusion
Molecular Sequence Data
Mutation

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