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A catalog of numerical centrosome defects in epithelial ovarian cancers

7 Sept 2022

Abstract excerpt

Centrosome amplification, the presence of more than two centrosomes in a cell is a common feature of most human cancer cell lines. However, little is known about centrosome numbers in human cancers and whether amplification or other numerical aberrations are frequently present. To address this question, we have analyzed a large cohort of primary human epithelial ovarian cancers (EOCs) from 100 patients. We found...

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PMID: 36069081
DOI: 10.15252/emmm.202215670

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