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Article

8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells.

Cancer research - 15 Dec 2002

Parker Antony R, O'Meally Robert N, Oliver Dwight H, Hua Li, Nelson William G, DeWeese Theodore L, Eshleman James R

Abstract excerpt

Mutator phenotypes are involved in the carcinogenesis of some cancers, e.g., defects in mismatch repair produce a mutator phenotype that drives carcinogenesis and causes microsatellite instability in hereditary nonpolyposis colon cancers and some sporadic colorectal cancers (CRC). Less understood, however, is the potential role of mutator phenotypes in microsatellite stable (MSS) CRC carcinogenesis. A novel...

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PMID: 12499263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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