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Article

Chemotherapeutic implications in microsatellite unstable colorectal cancer1

21 Jun 2006

Abstract excerpt

Chemotherapy for colorectal cancer is currently offered to patients based on the stage of their cancer, and there is evidence to show an overall survival benefit with 5-fluorouracil-based (5-FU) therapy for patients with lymph node metastasis who receive it. The pathogenesis of colorectal cancer involves genomic instability, with about 15% of tumors demonstrating a form of genomic instability called...

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PMID: 17192059
DOI: 10.3233/cbm-2006-21-206

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