Article
Is NF-kappaB2/p100 a direct activator of programmed cell death?
Cancer cell - 1 Dec 2002
Häcker Hans, Karin Michael
Abstract excerpt
Transcription factor NF-kappaB has been implicated in cancer development due to its ability to upregulate expression of genes with potentially prooncogenic functions, such as cell cycle regulators and antiapoptotic proteins (Karin et al., 2002). A recent report by suggests that a structural motif, a death domain (DD), present in one of the mammalian NF-kappaB proteins, NF-kappaB2/p100, allows it to directly...
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