Interaction of Ler at the LEE5 ( tir ) Operon of Enteropathogenic Escherichia coli

doi:10.1128/iai.71.1.384-392.2003

Article

Interaction of Ler at the LEE5 ( tir ) Operon of Enteropathogenic Escherichia coli

20 Dec 2002

Abstract excerpt

The genome of enteropathogenic Escherichia coli (EPEC) encodes a global regulator, Ler (locus of enterocyte effacement [LEE]-encoded regulator), which activates expression of several polycistronic operons within the 35.6-kb LEE pathogenicity island, including the LEE2-LEE3 divergent operon pair containing overlapping -10 regions and the LEE5 (tir) operon. Ler is a predicted 15-kDa protein that exhibits amino acid...

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