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Article

Antiviral activity of shiga toxin requires enzymatic activity and is associated with increased permeability of the target cells.

Infection and immunity - 1 Jan 2003

Basu Indira, Ferens Witold A, Stone Diana M, Hovde Carolyn J

Abstract excerpt

This study expanded our earlier finding that Shiga toxin type 1 (Stx1) has activity against bovine leukemia virus (BLV) (W. A. Ferens and C. J. Hovde, Infect. Immun. 68:4462-4469, 2000). The Stx molecular motifs required for antiviral activity were identified, and a mechanism of Stx action on virally infected cells is suggested. Using inhibition of BLV-dependent spontaneous lymphocyte proliferation as a measure...

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Source

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Identifiers

PMID: 12496182
DOI: 10.1128/IAI.71.1.327-334.2003
PMCID: PMC143405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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