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Article

Two-component systems in Haemophilus influenzae: a regulatory role for ArcA in serum resistance.

Infection and immunity - 1 Jan 2003

De Souza-Hart J A, Blackstock W, Di Modugno V, Holland I B, Kok M

Abstract excerpt

Knockout mutations were constructed in the arcA gene of a virulent type b strain of Haemophilus influenzae, and the behavior of the resulting mutants was investigated in a number of conditions that mimicked distinct steps in the natural infection pathway. In arcA mutants, synthesis of capsule and lipooligosaccharide (LOS) and growth in synthetic media were unaltered compared to synthesis of capsule and LOS and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Bactericidal Activity

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Identifiers

PMID: 12496162
DOI: 10.1128/IAI.71.1.163-172.2003
PMCID: PMC143216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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