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Article

The SaeRS Two-Component System Controls Survival of Staphylococcus aureus in Human Blood through Regulation of Coagulase.

Frontiers in cellular and infection microbiology - 1 Jan 2017

Guo Haiyong, Hall Jeffrey W, Yang Junshu, Ji Yinduo

Abstract excerpt

The SaeRS two-component system plays important roles in regulation of key virulence factors and pathogenicity. In this study, however, we found that the deletion mutation of saeRS enhanced bacterial survival in human blood, whereas complementation of the mutant with SaeRS returned survival to wild-type levels. Moreover, these phenomena were observed in different MRSA genetic background isolates, including HA-MRSA...

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Identifiers

PMID: 28611950
DOI: 10.3389/fcimb.2017.00204
PMCID: PMC5447086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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