Article
Apolipoprotein E and presenilin-1 allelic variation and Alzheimer's disease in India.
Human biology - 1 Oct 2002
Chandak G R, Sridevi M Uma, Vas C J, Panikker D M, Singh L
Abstract excerpt
As part of a larger epidemiological survey to study the prevalence of dementia in a suburb of Mumbai, Western India, we identified 78 cases with a Clinical Dementia Rating (CDR) > or = 1.0. Of these, 49 Alzheimer's disease (AD) cases were analyzed for risk association with APOE E*4 allele at apolipoprotein E gene (APOE) and presenilin-1 (PS-1) intron-8 polymorphism and were compared with 100 age- and sex-matched...
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