Article
Mining protein sequences for motifs.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2002
Narasimhan Giri, Bu Changsong, Gao Yuan, Wang Xuning, Xu Ning, Mathee Kalai
Abstract excerpt
We use methods from Data Mining and Knowledge Discovery to design an algorithm for detecting motifs in protein sequences. The algorithm assumes that a motif is constituted by the presence of a "good" combination of residues in appropriate locations of the motif. The algorithm attempts to compile such good combinations into a "pattern dictionary" by processing an aligned training set of protein sequences. The...
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