Article
Detecting cryptically simple protein sequences using the SIMPLE algorithm.
Bioinformatics (Oxford, England) - 1 May 2002
Albà M Mar, Laskowski Roman A, Hancock John M
Abstract excerpt
MOTIVATION: Low-complexity or cryptically simple sequences are widespread in protein sequences but their evolution and function are poorly understood. To date methods for the detection of low complexity in proteins have been directed towards the filtering of such regions prior to sequence homology searches but not to the analysis of the regions per se. However, many of these regions are encoded by non-repetitive...
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