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Article

Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter.

Human genetics - 1 Jan 2003

Hansen Jens J, Bross Peter, Westergaard Majken, Nielsen Marit Nyholm, Eiberg Hans, Børglum Anders D, Mogensen Jens, Kristiansen Karsten, Bolund Lars, Gregersen Niels

Abstract excerpt

Although the mitochondrial chaperonin Hsp60 and its co-chaperonin Hsp10 have received great attention in the last decade, and it has been proposed that mutations and variations in these genes may be implicated in genetic diseases, the genome structure of the human HSP60 and HSP10 genes (also known as HSPD1 and HSPE1, respectively) has not been firmly established. The picture has been confused by the presence of...

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Identifiers

PMID: 12483302
DOI: 10.1007/s00439-002-0837-9

Genes

HSPD1
HSPE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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