Article
Variations in MLL amplification in a patient with acute myeloid leukemia.
Leukemia & lymphoma - 1 Oct 2002
Brezinová Jana, Zemanová Zuzana, Cermák Jaroslav, Kurková Sárka, Sindelárová Lenka, Schwarz Jirí, Michalová Kyra
Abstract excerpt
In a 66 years old female patient with acute myeloblastic leukemia (AML) complex chromosomal rearrangements involving 11q23 were diagnosed by G-banding and confirmed by different fluorescence in situ hybridization (FISH) techniques. The amplification of MLL gene differed in various sidelines as shown by locus specific probes for 11q23 and 11q13. Complex karyotype rearrangements involving deletions del(5)(q31) and...
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