Article
MLL amplification in myeloid leukemias: A study of 14 cases with multiple copies of 11q23
1 Sept 2000
Abstract excerpt
We here report the clinical, cytogenetic, fluorescence in situ hybridization (FISH), and Southern blot data on 14 patients with a myeloid malignancy and structural aberration of chromosome band 11q23 associated with overrepresentation or amplification of the MLL gene. The number of copies of MLL varied from three (two cases) to a cluster consisting of multiple hybridization spots. Together with previous reports,...
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