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[Clinical Significance of Common Gene Mutations in 53 Patients with Acute Myeloid Leukemia Harboring 11q23/MLL Rearrangements].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2020

Bai Shu-Xiao, Gong Yan-Lei, Zhang Jing-Ren, Wu Chun-Xiao, Zhang Jun, Qiu Hui-Ying, Shen Hong-Jie, Cen Jian-Nong, Chen Su-Ning, Pan Jin-Lan

Abstract excerpt

OBJECTIVE: To investigate the clinical significance of AML patients with 11q23/MLL rearrangement, and to evaluate the effect of those mutations on the AML patients. METHODS: 53 cases involving translocations of chromosome 11q23 were identified by chromosome banding analysis. MLL rearrangements were detected by fluorescence in situ hybridization and/or multiplex nested PCR. The samples were screened for mutations...

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Share to Chromosomes, Human, Pair 11
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Transplantation

Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Myeloid, Acute

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Identifiers

PMID: 32552926
DOI: 10.19746/j.cnki.issn.1009-2137.2020.03.001

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