Article
Genetic analysis of vascular factors in Alzheimer's disease.
Annals of the New York Academy of Sciences - 1 Nov 2002
Wakutani Yosuke, Kowa Hisanori, Kusumi Masayoshi, Yamagata Kaoru, Wada-Isoe Kenji, Adachi Yoshiki, Takeshima Takao, Urakami Katsuya, Nakashima Kenji
Abstract excerpt
Genetic risk factors for Alzheimer's disease (AD) have been extensively examined. Several risk factors for AD are shared with vascular dementia (VaD). We performed genetic case-control studies on polymorphisms of the apolipoprotein E (ApoE) gene, the methylene tetrahydrofolate reductase (MTHFR) gene, and the angiotensin-converting enzyme (ACE) gene. The most acceptable genetic risk factor for the development of...
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