Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects.

Current Alzheimer research - 1 Jun 2009

Rocchi A, Orsucci D, Tognoni G, Ceravolo R, Siciliano G

Abstract excerpt

Alzheimer's disease (AD) is a late-onset progressive neurodegenerative disorder which results in the irreversible loss of cortical neurons, particularly in the associative neocortex and hippocampus. AD is the most common form of dementia in the elderly. Apart from the neuronal loss, the pathological hallmarks are extracellular senile plaques, containing the peptide beta-amyloid (Abeta), and neurofibrillary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Signaling Peptides and Proteins

Share to Models, Biological

Share to Peptides

Share to Plaque, Amyloid

Share to Risk Factors

Source

Identifiers

PMID: 19519304
DOI: 10.2174/156720509788486644

Genes

CST3
MTHFR
NOS3
OLR1
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects.PMID 19519304Read ↗

Vascular risk and genetics of sporadic late-onset Alzheimer’s diseaseSemantic proximity Read ↗

[Genetics of late-onset Alzheimer's disease: vascular risk and beta-amyloid metabolism].Semantic proximity Read ↗

[Vascular risk factors and Alzheimer disease risk: epidemiological studies review].Semantic proximity Read ↗

Cerebrovascular risk factors in Alzheimer's disease: brain hemodynamics and pharmacogenomic implications.Semantic proximity Read ↗

Genetic Determinants of Vascular Dementia.Semantic proximity Read ↗

Current insights into molecular mechanisms of Alzheimer disease and their implications for therapeutic approaches.Semantic proximity Read ↗

Interplay Between Vascular Dysfunction and Neurodegenerative Pathology: New Insights into Molecular Mechanisms and ManagementSemantic proximity Read ↗

Multiple substrates of late-onset dementia: implications for brain protection.Semantic proximity Read ↗

Genetic dissection of susceptibility to vascular dementia.Semantic proximity Read ↗

Is apolipoprotein E4 an important risk factor for vascular dementia?Semantic proximity Read ↗

Genetic Variants behind Cardiovascular Diseases and Dementia.Semantic proximity Read ↗

The influence of coincidental vascular pathology on symptomatology and course of Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.