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Article

Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans.

Molecular genetics and metabolism - 1 Mar 2015

Oppelt Sarah A, Sennott Erin M, Tolan Dean R

Abstract excerpt

The rise in fructose consumption, and its correlation with symptoms of metabolic syndrome (MBS), has highlighted the need for a better understanding of fructose metabolism. To that end, valid rodent models reflecting the same metabolism as in humans, both biochemically and physiologically, are cr...

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PMID: 25637246
DOI: 10.1016/j.ymgme.2015.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25637246-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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