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Article

No evidence for association of ataxia-telangiectasia mutated gene T2119C and C3161G amino acid substitution variants with risk of breast cancer.

Breast cancer research : BCR - 1 Jan 2002

Spurdle Amanda B, Hopper John L, Chen Xiaoqing, McCredie Margaret R E, Giles Graham G, Newman Beth, Chenevix-Trench Georgia, Khanna KumKum

Abstract excerpt

BACKGROUND: There is evidence that certain mutations in the double-strand break repair pathway ataxia-telangiectasia mutated gene act in a dominant-negative manner to increase the risk of breast cancer. There are also some reports to suggest that the amino acid substitution variants T2119C Ser707Pro and C3161G Pro1054Arg may be associated with breast cancer risk. We investigate the breast cancer risk associated...

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Identifiers

PMID: 12473176
DOI: 10.1186/bcr534
PMCID: PMC137935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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