Article
Genetic association analysis using microsatellite markers in atopic dermatitis.
The Tokai journal of experimental and clinical medicine - 1 Aug 2002
Iizuka Mariko, Katsuyama Yoshihiko, Mabuchi Tomotaka, Umezawa Yoshinori, Matsuyama Takashi, Ozawa Akira, Kawada Hisako, Inoko Hidetoshi, Morita Eishin, Ota Masao
Abstract excerpt
Atopic dermatitis (AD) is presumed to be influenced by genetic and environmental factors. In this study, 54 patients with AD were examined for disease association by the use of 12 microsatellite markers. Several significant associations were recognized in the alleles on chromosome 5, 7 and 11. AD genes were mapped near the FC epsilon RI beta gene (around D11S1314 locus) on chromosome 11, the IL4 gene cluster on...
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