Article
Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population.
Allergy - 1 May 2006
Bu L M, Bradley M, Söderhäll C, Wahlgren C F, Kockum I, Nordenskjold M
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a hereditary, pruritic, chronic, relapsing, inflammatory skin disease resulting from multiplex interactions between genes and environmental factors. We have previously found several loci showing suggestive linkage on chromosomes 3q14, 13q14, 15q14-15 and 17q21, and weaker linkage to chromosomes 1p32, 4q24-26 and 21q21 in 109 Swedish families. METHODS: In order to confirm the...
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