Article
Linkage disequilibrium in the 13q12 region in Finnish late onset Alzheimer's disease patients.
European journal of human genetics : EJHG - 1 Sept 1999
Hiltunen M, Mannermaa A, Koivisto A M, Lehtovirta M, Helisalmi S, Ryynänen M, Riekkinen P, Soininen H
Abstract excerpt
Alzheimer's disease (AD) is a complex neurodegenerative disorder, for which several disease-associated loci have been located on different chromosomes. We have used a population-based linkage disequilibrium mapping approach in order to find potential AD-associated loci on chromosome 13. To avoid population stratification, late onset AD patients and age-matched controls were carefully chosen from the same...
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