Article
Beta2-microglobulin aberrations in diffuse large B-cell lymphoma of the testis and the central nervous system.
International journal of cancer - 20 Jan 2003
Jordanova Ekaterina S, Riemersma Sietske A, Philippo Katja, Schuuring Ed, Kluin Philip M
Abstract excerpt
Human leukocyte antigen (HLA) class I molecules are expressed on the surface of all nucleated cells and present antigenic peptides to cytotoxic T cells, thereby playing an important role in initiating the cellular anti-tumor immune response. We previously reported that loss of HLA class I expression in diffuse large B-cell lymphoma (DLBCL) of the central nervous system (CNS) and the testis is a common event. Loss...
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