Article
Characterization and comparative functional analysis in yeast of a Schistosoma mansoni Rho1 GTPase gene.
Molecular and biochemical parasitology - 1 Jan 2000
Santos Túlio Marcos, Machado Carlos Renato, Franco Glória Regina, Pena Sérgio Danilo Junho
Abstract excerpt
Low-molecular weight GTP-binding proteins (LMWGPs) of the Ras superfamily are believed to play a role in Schistosoma mansoni female development and egg production. Here we describe the characterization of a novel S. mansoni gene (SMRHO1), highly homologous to Rho-type LMWGPs from several other organisms and encoding a polypeptide with 193 amino acids and an estimated molecular mass of 21.8 kDa. SMRHO1...
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