Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tum1 is involved in the metabolism of sterol esters in Saccharomyces cerevisiae.

BMC microbiology - 22 Aug 2017

Uršič Katja, Ogrizović Mojca, Kordiš Dušan, Natter Klaus, Petrovič Uroš

Abstract excerpt

BACKGROUND: The only hitherto known biological role of yeast Saccharomyces cerevisiae Tum1 protein is in the tRNA thiolation pathway. The mammalian homologue of the yeast TUM1 gene, the thiosulfate sulfurtransferase (a.k.a. rhodanese) Tst, has been proposed as an obesity-resistance and antidiabetic gene. To assess the role of Tum1 in cell metabolism and the putative functional connection between lipid metabolism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Esters
Share to Gene Deletion
Share to Lipid Metabolism

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lipids

Share to RNA, Transfer

Share to Saccharomyces cerevisiae Proteins

Share to Sterols

Share to Vertebrates

Source

Open in PubMed Open full text

Identifiers

PMID: 28830344
DOI: 10.1186/s12866-017-1088-1
PMCID: PMC5567475

Genes

TST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tum1 is involved in the metabolism of sterol esters in Saccharomyces cerevisiae.PMID 28830344Read ↗

The thioredoxin system protects ribosomes against stress-induced aggregation.Semantic proximity Read ↗

Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants.Semantic proximity Read ↗

A putative role for Mrx3 and Fmp10 in regulating yeast mitochondrial acyl-CoA thioesters.Semantic proximity Read ↗

Identification of lethal mutations in yeast threonyl-tRNA synthetase revealing critical residues in its human homolog.Semantic proximity Read ↗

tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae.Semantic proximity Read ↗

Loss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutants.Semantic proximity Read ↗

Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation.Semantic proximity Read ↗

A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism.Semantic proximity Read ↗

Urm1: A Non-Canonical UBL.Semantic proximity Read ↗

Thiosulfate sulfurtransferase-like domain-containing 1 protein interacts with thioredoxin.Semantic proximity Read ↗

Characterization of the Saccharomyces cerevisiae RTA1 gene involved in 7-aminocholesterol resistance.Semantic proximity Read ↗

A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.