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Article

Negative functional interaction between cell integrity MAPK pathway and Rho1 GTPase in fission yeast.

Genetics - 1 Oct 2013

Viana Raul A, Pinar Mario, Soto Teresa, Coll Pedro M, Cansado Jose, Pérez Pilar

Abstract excerpt

Rho1 GTPase is the main activator of cell wall glucan biosynthesis and regulates actin cytoskeleton in fungi, including Schizosaccharomyces pombe. We have obtained a fission yeast thermosensitive mutant strain carrying the rho1-596 allele, which displays reduced Rho1 GTPase activity. This strain has severe cell wall defects and a thermosensitive growth, which is partially suppressed by osmotic stabilization. In a...

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Identifiers

PMID: 23934882
DOI: 10.1534/genetics.113.154807
PMCID: PMC3781970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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