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Article

Lack of mitochondrial citrate synthase discloses a new meiotic checkpoint in a strict aerobe.

The EMBO journal - 2 Dec 2002

Ruprich-Robert Gwenaël, Zickler Denise, Berteaux-Lecellier Véronique, Vélot Christian, Picard Marguerite

Abstract excerpt

Mitochondrial citrate synthase (mCS) is the initial enzyme of the tricarboxylic acid (TCA) cycle. Despite the key position of this protein in respiratory metabolism, very few studies have addressed the question of the effects of the absence of mCS in development. Here we report on the characterization of 15 point mutations and a complete deletion of the cit1 gene, which encodes mCS in the filamentous fungus...

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Identifiers

PMID: 12456651
DOI: 10.1093/emboj/cdf632
PMCID: PMC136936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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