Article
Variation at the beta-1 adrenoceptor gene locus affects left ventricular mass in renal failure.
Journal of nephrology - 1 Jan 2000
Stanton Tony, Inglis Gordon C, Padmanabhan Sandosh, Dominiczak Anna F, Jardine Alan G, Connell John M C
Abstract excerpt
OBJECTIVES: To examine the relationship between this variation in the beta1AR gene and the effect on LV mass. BACKGROUND: Left ventricular (LV) mass is an important cardiovascular risk factor. Beta-1 adrenoceptors (betaAR) are predominately located in the heart and their variation may, therefore, affect LV mass. A known polymorphism of the betaAR changes the amino acid at position 389 from glycine to arginine...
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