Article
alphaNAC requires an interaction with c-Jun to exert its transcriptional coactivation.
Gene expression - 1 Jan 2002
Quèlo Isabelle, Hurtubise Mélanie, St-Arnaud René
Abstract excerpt
alphaNAC is a transcriptional coactivator known to interact with the N-terminal activation domain of the c-Jun transcription factor. In this article, we describe the identification of the c-Jun interaction domain within the alphaNAC protein. Deletion analysis of alphaNAC indicated that the c-Jun binding site was located in the middle part of the protein, between residues 89 and 129. The deletion of the C-terminal...
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