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Article

Polymorphisms in the interleukin-1 (IL1) gene cluster are not associated with aggressive periodontitis in a large Caucasian population.

Genomics - 1 Nov 2008

Fiebig Andreas, Jepsen Søren, Loos Bruno G, Scholz Claudia, Schäfer Christine, Rühling Andreas, Nothnagel Michael, Eickholz Peter, van der Velden Ubele, Schenck Karl, Schreiber Stefan, Grössner-Schreiber Birte

Abstract excerpt

Polymorphisms in the interleukin-1 (IL1) gene have been suggested to influence transcription of IL1A (interleukin-1alpha) and IL1B (interleukin-1beta) and thereby the pathophysiology of periodontitis. This case-control association study on 415 northern European Caucasian patients with aggressive periodontitis (AgP) and 874 healthy controls was conducted to examine 10 single-nucleotide polymorphisms (SNPs) in the...

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PMID: 18723088
DOI: 10.1016/j.ygeno.2008.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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