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Article

Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 May 2010

Zhang Guo-xi, Wang Bao-jun, Ouyang Jin-zhi, Deng Xi-yuan, Ma Xin, Li Hong-zhao, Wu Zhun, Liu Shuang-lin, Xu Hua, Zhang Xu

Abstract excerpt

Several frequent polymorphisms in the CYP11B2 gene are suggested to be associated with essential hypertension and aldosterone secretion. In this study, we investigated the association of polymorphisms in CYP11B2 and CYP11B1 genes with the risk of primary hyperaldosteronism (PH). Three polymorphisms in the CYP11B2 gene (intron 2 conversion, rs1799998 and rs4539) and two polymorphisms in the CYP11B1 gene (rs6410...

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Identifiers

PMID: 20339375
DOI: 10.1038/hr.2010.21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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