Article
Functional consequences of the in-frame insertion of a transposon into the mutated gamma amino butyric acid transporter of Saccharomyces cerevisiae.
Medical science monitor : international medical journal of experimental and clinical research - 1 Nov 2002
Naghibalhossaini Fakhraddin, Nault Francine, Saragovi Uri, Nedev Haynu, Johnstone Rose
Abstract excerpt
BACKGROUND: The Saccharomyces cerevisiae strain, 22574d, lacks gamma amino butyric acid (GABA) transport activity and cannot grow on this amino acid as sole nitrogen source. Both transport of and growth on this amino acid are restored when the yeast is transformed with a form of mouse gamma actin containing an extended C-terminal sequence (M-g-A). The nature of the mutation in the transporter as well as the...
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