Article
Is gamma-actin a regulator of amino acid transport?
The American journal of physiology - 1 Jun 1996
Lin G, McCormick J I, Johnstone R M
Abstract excerpt
A mutated yeast cell line incapable of growth in minimal medium with proline as the sole nitrogen source was restored to normal growth by transfection with a cDNA from mouse Ehrlich cells. The cloned cDNA (E51) was found to be 90% homologous to gamma-actin. Immediately after transfection with E51 cDNA, both alpha-aminoisobutyric acid (AIB) and proline uptake in the mutated yeast were increased, particularly at pH...
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