Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the Saccharomyces cerevisiae RTA1 gene involved in 7-aminocholesterol resistance.

Current genetics - 31 Jul 1996

Soustre I, Letourneux Y, Karst F

Abstract excerpt

7-aminocholesterol has been described as being a strong inhibitor of yeast and of Gram+-bacteria proliferation. In order to determine the precise molecular target of the toxicity of this compound, we searched for yeast resistance linked to gene over-expression. We named the new yeast gene that wa...

Topics

Amino Acid Sequence
Antifungal Agents
Cholesterol
Cloning, Molecular
Drug Resistance, Microbial
Fungal Proteins
Genes, Fungal
Membrane Proteins
Molecular Sequence Data
Mutagenesis
Phenotype
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae Proteins

Sterols

Source

Identifiers

PMID: 8660468
DOI: 10.1007/s002940050110

Genes

NAB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8660468-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the Saccharomyces cerevisiae RTA1 gene involved in 7-aminocholesterol resistance.PMID 8660468Read ↗

Tum1 is involved in the metabolism of sterol esters in Saccharomyces cerevisiae.Semantic proximity Read ↗

A cytoplasmic factor involved in the expression of resistance to C8-ATC in Saccharomyces cerevisiae.Semantic proximity Read ↗

Identification of essential yeast genes involved in polyamine resistance.Semantic proximity Read ↗

Allelism of SNQ1 and ATR1, genes of the yeast Saccharomyces cerevisiae required for controlling sensitivity to 4-nitroquinoline-N-oxide and aminotriazole.Semantic proximity Read ↗

Commonly used Saccharomyces cerevisiae strains (e.g. BY4741, W303) are growth sensitive on synthetic complete medium due to poor leucine uptake.Semantic proximity Read ↗

Isolation and characterization of the Saccharomyces cerevisiae SUT1 gene involved in sterol uptake.Semantic proximity Read ↗

Terbinafine resistance in a pleiotropic yeast mutant is caused by a single point mutation in the ERG1 gene.Semantic proximity Read ↗

Identification of the TPO1 gene in yeast, and its human orthologue TETRAN, which cause resistance to NSAIDs.Semantic proximity Read ↗

KNQ1, a Kluyveromyces lactis gene encoding a drug efflux permease.Semantic proximity Read ↗

Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3.Semantic proximity Read ↗

Yeast gene YRR1, which is required for resistance to 4-nitroquinoline N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2.Semantic proximity Read ↗

Alkyl hydroperoxide reductase 1 protects Saccharomyces cerevisiae against metal ion toxicity and glutathione depletion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.