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Article

Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer.

Journal of the National Cancer Institute - 20 Nov 2002

Chang Hsueh-Wei, Lee Shing M, Goodman Steven N, Singer Gad, Cho Sarah K R, Sokoll Lori J, Montz Fredrick J, Roden Richard, Zhang Zhen, Chan Daniel W, Kurman Robert J, Shih Ie-Ming

Abstract excerpt

BACKGROUND: Allelic imbalance (AI), the loss or gain of chromosomal regions, is found in many cancers. AI can be detected in genomic tumor DNA released into the blood after necrosis or apoptosis. We evaluated plasma DNA concentration, allelic status in plasma DNA, and serum CA 125 level as screening tests for ovarian and other cancers. METHODS: Plasma samples were obtained from 330 women (44 normal healthy...

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Identifiers

PMID: 12441325
DOI: 10.1093/jnci/94.22.1697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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