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Article

Evolution of total and integrated HIV-1 DNA and change in DNA sequences in patients with sustained plasma virus suppression.

Virology - 25 Oct 2002

Izopet Jacques, Cazabat Michèle, Pasquier Christophe, Sandres-Sauné Karine, Bonnet Eric, Marchou Bruno, Massip Patrice, Puel Jacqueline

Abstract excerpt

Blood samples from patients with plasma HIV-1 RNA <20 copies/ml for more than 2 years were studied. Significant decreases in total and integrated HIV-1 DNA were observed during the first 15 months of suppressive therapy before the concentrations became stable. Clonal analysis of HIV-1 pol demonstrated that the proportions of resistance mutations in DNA sequences after 2 years were lower than those in baseline DNA...

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Source

Identifiers

PMID: 12441083
DOI: 10.1006/viro.2002.1621

Genes

CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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