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Article

Phenotypic and genotypic analysis of biologically cloned human immunodeficiency virus type 1 isolates from patients treated with zidovudine and lamivudine.

Antimicrobial agents and chemotherapy - 1 Dec 2002

Stoeckli Thomas C, MaWhinney Samantha, Uy Jonathan, Duan Chengying, Lu Jing, Shugarts David, Kuritzkes Daniel R

Abstract excerpt

Mutations at reverse transcriptase codons 44, 118, 207, and 208 were significantly correlated with reduced zidovudine susceptibility in biologically cloned human immunodeficiency virus type 1 (HIV-1) isolates. Sequences from the Stanford HIV RT and Protease Sequence Database showed that these mutations were more common in HIV-1 isolates from patients treated with zidovudine and lamivudine than in patients not...

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Identifiers

PMID: 12435711
DOI: 10.1128/AAC.46.12.4000-4003.2002
PMCID: PMC132743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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