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Article

Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 26 Nov 2002

Deutschbauer Adam M, Williams Roy M, Chu Angela M, Davis Ronald W

Abstract excerpt

We have quantitatively monitored the sporulation and germination efficiencies of approximately 4,200 yeast deletion strains in parallel by using a molecular bar coding strategy. In a single study, we doubled the number of genes functionally implicated in sporulation to approximately 400, identifying both positive and negative regulators. Our set of 261 sporulation-deficient genes illustrates the importance of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12432101
DOI: 10.1073/pnas.202604399
PMCID: PMC137751

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Source receipt: pubmed, retrieved 7 Sept 2026.

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