Article
Stage-specific requirement of a mitogen-activated protein kinase by Trypanosoma brucei.
Molecular biology of the cell - 1 Nov 2002
Müller Ingrid B, Domenicali-Pfister Debora, Roditi Isabel, Vassella Erik
Abstract excerpt
In cycling between the mammalian host and the tsetse fly vector, African trypanosomes undergo adaptive differentiation steps that are coupled to growth control. The signaling pathways underlying these cellular processes are largely unknown. Mitogen-activated protein kinases (MAPKs) are known mediators of growth and differentiation in other eukaryotic organisms. To establish the function of a MAPK homologue,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.