Article
Life-cycle differentiation in Trypanosoma brucei: molecules and mutants.
Biochemical Society transactions - 1 Oct 2000
Hendriks E, van Deursen F J, Wilson J, Sarkar M, Timms M, Matthews K R
Abstract excerpt
Differentiation between bloodstream and tsetse midgut procyclic forms during the life cycle of the African trypanosome is an attractive model for the analysis of stage-regulated events. In particular, this transformation occurs synchronously, there are well-defined markers for stage-regulated processes and cell lines with specific defects in differentiation have been identified. This combination of tools,...
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