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Article

NisB is required for the dehydration and NisC for the lanthionine formation in the post-translational modification of nisin.

Microbiology (Reading, England) - 1 Nov 2002

Koponen Olli, Tolonen Marja, Qiao Mingqiang, Wahlström Gudrun, Helin Jari, Saris Per E J

Abstract excerpt

Nisin produced by Lactococcus lactis subsp. lactis is a 34-residue antibacterial polypeptide and belongs to a group of post-translationally modified peptides, lantibiotics, with dehydrated residues and cyclic amino acids, lanthionines. These modifications are supposed to be made by enzymes encoded by lanB and lanC genes, found only in biosynthetic operons encoding lantibiotics. To analyse the extent of...

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PMID: 12427947
DOI: 10.1099/00221287-148-11-3561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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