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Article

Regulation of the nisin operons in Lactococcus lactis N8.

The Journal of applied bacteriology - 1 Jun 1996

Qiao M, Ye S, Koponen O, Ra R, Usabiaga M, Immonen T, Saris P E

Abstract excerpt

The antibiotic peptide nisin produced by Lactococcus lactis is used as a food preservative due to its activity against spores and vegetative cells of Gram-positive bacteria. The post-translational maturation of this secreted peptide includes dehydration of serine and threonine residues, lanthionine formation and a proteolytic processing of 23 amino acids from the N-terminus. Mutations in the nisZ, nisB and nisP...

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Source

Identifiers

PMID: 8698664
DOI: 10.1111/j.1365-2672.1996.tb03267.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of the nisin operons in Lactococcus lactis N8.PMID 8698664Read ↗

Evidence for a role of NisT in transport of the lantibiotic nisin produced by Lactococcus lactis N8.Semantic proximity Read ↗

Investigation of genes involved in nisin production in Enterococcus spp. strains isolated from raw goat milk.Semantic proximity Read ↗

Genes involved in immunity to the lantibiotic nisin produced by Lactococcus lactis 6F3.Semantic proximity Read ↗

NisB is required for the dehydration and NisC for the lanthionine formation in the post-translational modification of nisin.Semantic proximity Read ↗

Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance.Semantic proximity Read ↗

Nisin induction without nisin secretion.Semantic proximity Read ↗

Substrate Specificity of the Secreted Nisin Leader Peptidase NisP.Semantic proximity Read ↗

Protein Defense Systems against the Lantibiotic Nisin: Function of the Immunity Protein NisI and the Resistance Protein NSRSemantic proximity Read ↗

NSR from <i>Streptococcus agalactiae</i> confers resistance against nisin and is encoded by a conserved <i>nsr</i> operonSemantic proximity Read ↗

Properties of nisin Z and distribution of its gene, nisZ, in Lactococcus lactis.Semantic proximity Read ↗

Characterization of the promoter regions involved in galactose- and nisin-mediated induction of the nisA gene in Lactococcus lactis ATCC 11454.Semantic proximity Read ↗

Use of the Lactococcal <i>nisA</i> Promoter To Regulate Gene Expression in Gram-Positive Bacteria: Comparison of Induction Level and Promoter StrengthSemantic proximity Read ↗

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