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Article

Identification of essential catalytic residues of the cyclase NisC involved in the biosynthesis of nisin.

The Journal of biological chemistry - 20 Jul 2007

Li Bo, van der Donk Wilfred A

Abstract excerpt

Nisin is a post-translationally modified antimicrobial peptide that has been widely used in the food industry for several decades. It contains five cyclic thioether cross-links of varying sizes that are installed by a single enzyme, NisC, that catalyzes the addition of cysteines to dehydroamino a...

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PMID: 17513866
DOI: 10.1074/jbc.M701802200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17513866-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of essential catalytic residues of the cyclase NisC involved in the biosynthesis of nisin.PMID 17513866Read ↗

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Evolutionary and functional analysis of an NRPS condensation domain integrates β-lactam, ᴅ-amino acid, and dehydroamino acid synthesisSemantic proximity Read ↗

First evidence of production of the lantibiotic nisin PSemantic proximity Read ↗

Evidence for a role of NisT in transport of the lantibiotic nisin produced by Lactococcus lactis N8.Semantic proximity Read ↗

Regulation of the nisin operons in Lactococcus lactis N8.Semantic proximity Read ↗

Protein Defense Systems against the Lantibiotic Nisin: Function of the Immunity Protein NisI and the Resistance Protein NSRSemantic proximity Read ↗

Structural basis of lantibiotic recognition by the nisin resistance protein from Streptococcus agalactiae.Semantic proximity Read ↗

Towards improved resistance of <i>Corynebacterium glutamicum</i> against nisinSemantic proximity Read ↗

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