Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease.

Acta neurologica Taiwanica - 1 Sept 2007

Lin Juei-Jueng, Yueh Kuo-Chu, Liu Chin-San, Liu Jung-Tung, Lin Shinn-Zong

Abstract excerpt

A case-control study was designed to investigate a possible genetic susceptibility of the MTHFR C677T polymorphism and assess whether the genetic polymorphism could be a predictor of levodopa-induced adverse effects in patients with Parkinson's disease (PD) of Chinese descent living in Taiwan. There were 94 sporadic PD patients with levodopa therapy at least for five years and 146 control subjects, matched by sex...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Homocysteine

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Parkinson Disease

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 17966954

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease.PMID 17966954Read ↗

MTHFR C677T and A1298C polymorphisms may contribute to the risk of Parkinson's disease: A meta-analysis of 19 studies.Semantic proximity Read ↗

The MTHFR C677T polymorphism modifies age at onset in Parkinson's disease.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and susceptibility to Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

MTHFR C677T variant reduces risk of sporadic Parkinson's disease in ethnic Chinese.Semantic proximity Read ↗

The effect of onset age on the clinical features of Parkinson's disease.Semantic proximity Read ↗

Correlation of tau gene polymorphism with age at onset of Parkinson's disease.Semantic proximity Read ↗

Association of MTHFR C677T with total homocysteine plasma levels and susceptibility to Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

Association of MTHFR, MTR, and MTRR polymorphisms with Parkinson's disease among ethnic Chinese in Taiwan.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset.Semantic proximity Read ↗

Roles of gender, age at onset and environmental risk in the frequency of CYP2D6-deficient alleles in patients with Parkinson's disease.Semantic proximity Read ↗

SNCA: major genetic modifier of age at onset of Parkinson's disease.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and plasma homocysteine in levodopa-treated and non-treated Parkinson's disease patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.