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Article

Tissue localization of the copper chaperone ATOX1 and its potential role in disease.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2002

Moore Steven D P, Helmle Karmon E, Prat Lisa M, Cox Diane W

Abstract excerpt

ATOX1 is a cytoplasmic copper chaperone that interacts with the copper-binding domain of the membrane copper transporters ATP7A and ATP7B. ATOX1 has also been suggested to have a potential anti-oxidant activity. This study investigates the tissue-specific localization of the mouse homolog, Atox1, in mouse liver and kidney. Immunohistochemical studies in the liver localize the copper chaperone to hepatocytes...

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Source

Identifiers

PMID: 12420134
DOI: 10.1007/s00335-002-2172-9

Genes

ATOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Tissue localization of the copper chaperone ATOX1 and its potential role in disease.PMID 12420134Read ↗

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