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Article

Visualization of the intracellular behavior of HIV in living cells

4 Nov 2002

Abstract excerpt

To track the behavior of human immunodeficiency virus (HIV)-1 in the cytoplasm of infected cells, we have tagged virions by incorporation of HIV Vpr fused to the GFP. Observation of the GFP-labeled particles in living cells revealed that they moved in curvilinear paths in the cytoplasm and accumulated in the perinuclear region, often near the microtubule-organizing center. Further studies show that HIV uses...

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PMID: 12417576
DOI: 10.1083/jcb.200203150

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