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How HIV-1 Takes Advantage of the Cytoskeleton during Replication and Cell-to-Cell Transmission

15 Sept 2011

Abstract excerpt

Human immunodeficiency virus 1 (HIV-1) infects T cells, macrophages and dendritic cells and can manipulate their cytoskeleton structures at multiple steps during its replication cycle. Based on pharmacological and genetic targeting of cytoskeleton modulators, new imaging approaches and primary cell culture models, important roles for actin and microtubules during entry and cell-to-cell transfer have been...

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PMID: 21994805
DOI: 10.3390/v3091757

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