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Article

Microtubule-mediated Transport of Incoming Herpes Simplex Virus 1 Capsids to the Nucleus

10 Mar 1997

Abstract excerpt

Herpes simplex virus 1 fuses with the plasma membrane of a host cell, and the incoming capsids are efficiently and rapidly transported across the cytosol to the nuclear pore complexes, where the viral DNA genomes are released into the nucleoplasm. Using biochemical assays, immunofluorescence, and immunoelectron microscopy in the presence and absence of microtubule depolymerizing agents, it was shown that the...

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PMID: 9060466
DOI: 10.1083/jcb.136.5.1007

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