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HIV Infection: Shaping the Complex, Dynamic, and Interconnected Network of the Cytoskeleton

23 Aug 2023

Abstract excerpt

HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (i.e., actin and intermediate filaments (AFs and IFs) and microtubules (MTs)) to achieve the viral cycle. HIV-1 modifies cytoskeletal organization and dynamics by acting on associated adaptors and molecular motors to productively fuse, enter, and infect cells and then traffic to the cell surface, where virions assemble and are...

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PMID: 37685911
DOI: 10.3390/ijms241713104

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